Study of Brain Activity in Parkinson's and Epilepsy
Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement
Recruiting
N/AInterventional Study
Parkinson DiseaseEpilepsy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Health Services Research
Participants needed
30 (estimated)
Sponsor
University Hospital, Bordeaux · Other
Who this trial is looking for
This trial is looking for people with Parkinson's disease or epilepsy to study brain activity during simple movements. Participants will be asked to perform a motor task while being monitored.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 75 years old.
I have Parkinson's disease and have had surgery to implant electrodes.
I have drug-resistant epilepsy and am undergoing pre-surgical assessment.
I have at least one electrode in my brain area related to movement.
I can perform a simple motor task.
I agree to give written consent.
You may not be able to join if
I cannot give consent personally.
I am under legal protection.
I am pregnant or breastfeeding.
I have a serious physical or mental illness.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The expression of hypokinetic and hyperkinetic motor symptoms is accompanied by pathological synchronous oscillations of neuronal activity in this cortico-subcortical network with a wide frequency range.
The purpose of this research is to study cortico-subcortical oscillations and their synchronization in two pathologies emblematic of hypokinetic (Parkinson's disease) and hyperkinetic (epilepsies…
The expression of hypokinetic and hyperkinetic motor symptoms is accompanied by pathological synchronous oscillations of neuronal activity in this cortico-subcortical network with a wide frequency range.
The purpose of this research is to study cortico-subcortical oscillations and their synchronization in two pathologies emblematic of hypokinetic (Parkinson's disease) and hyperkinetic (epilepsies) phenomena using a simple motor task and comparing different situations.
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Eligibility Criteria
Inclusion criteria :
* Male or Female
* Between 18 and 75 years of age
* With Parkinson's disease and already operated with implantation of electrodes in the Subthalamic nucleus connected to a PERCEPT (TM) device.
* Giving free, informed, written consent signed by the participant and the investigat…
Inclusion criteria :
* Male or Female
* Between 18 and 75 years of age
* With Parkinson's disease and already operated with implantation of electrodes in the Subthalamic nucleus connected to a PERCEPT (TM) device.
* Giving free, informed, written consent signed by the participant and the investigator Or
* With drug-resistant epilepsy and benefiting from a phase II pre-surgical assessment with intracerebral electrophysiological exploration by stereo-EEG
* With at least one electrode exploring the basal ganglia or the thalamus.
* Able to perform the simple motor task
* Affiliated or beneficiary of a social security scheme;
* Giving free, informed, written consent signed by the participant and the investigator
Exclusion criteria:
* Be incapable of giving consent personally
* Be subject to a legal protection measure or be placed under judicial protection;
* Being pregnant or breastfeeding
* Present a serious and/or decompensated somatic or psychiatric illness
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