Benzodiazepine Impact on Cognitive Function: fNIRs and PET/MRI Study
Recruiting
Observational Study
Benzodiazepine Adverse Reaction
Depression, Anxiety
Benzodiazepine Dependence
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- The First Affiliated Hospital of Dalian Medical University · Other
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About This Trial
This study explores the impact of long-term benzodiazepine (BZDs) use on cognitive function and associated neuroimaging markers. While BZDs are established treatments for conditions like anxiety and insomnia, recent warnings highlight risks, including neurocognitive effects. Neuroimaging studies indicate potential neuroprotective effects of BZDs. Functional near-infrared spectroscopy (fNIRS) measu…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Continuous use of benzodiazepines for ≥3 months, matched with participants who have not taken benzodiazepines.
2. Education time ≥6 years.
3. Abstained from alcohol, coffee, and other psychoactive substances in the 24 hours before the examination.
Exclusion Criteria：
1. Bra…
Contacts