NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis

Recruiting Observational Study
Amyloidosis Amyloidosis Cardiac ATTR Amyloidosis Wild Type
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 99
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
Paolo Milani · Other
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About This Trial
All ATTRwt patients on tafamidis 61 mg treatment will be clinically evaluated before treatment initiation and subsequently every six months for the eligibility to continue tafamidis treatment, according to Italian Medicines Agency regulations. C onsidering the significant risk of developing heart rhythm disturbances due to cardiac amyloidosis, especially in transthyretin form (ATTRwt), in routine …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosis of ATTRwt amyloidosis. * 18 years or older; * evidence of cardiac involvement at echocardiography or cardiac MRI. * No known prior history of atrial fibrillation or major bradyarrhythmia (second degree atrioventricular block, third-degree atrioventricular block, high…
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