The Maintenance Treatment of "ITIVA" in AML Patients
Recruiting
N/A
Interventional Study
Acute Myeloid Leukemia
Maintenance Treatment
Minor Residue Disease
Interferon-α-1b
Interleukin-2
Thalidomide
Venentoclax
Azacitidine
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 14 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 130 (estimated)
- Sponsor
- Henan Cancer Hospital · Government
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About This Trial
We apply for this clinical study to evaluate the efficacy of "combined recombinant human interference'- α- 1b, interleukin-2, and thalidomide" regimen in obtaining MRD positive AML patients in CR,as well as the efficacy of the "Venentoclax and azacitidine" regimen and the "combined recombinant human interference'- α- 1b, interleukin-2, and thalidomide" regimen in alternately maintaining the treatm…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Male or female, ≥ 14 years old.
2. According to the WHO (2016) diagnostic criteria, the diagnosis of newly diagnosed AML is met (excluding APL).
3. After conventional induction and chemotherapy with at least two consolidation schemes (at least one cycle of the scheme containi…
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