Ga-PSMA PET/MRI for Liver Cirrhosis Assessment
Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis
Recruiting
Observational Study
Liver Cirrhosis
Hepatic Cell Carcinoma
Portal Hypertension
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 99
- Sex
- Any
- Study type
- Observational
- Participants needed
- 45 (estimated)
- Sponsor
- Massachusetts General Hospital · Other
Who this trial is looking for
This trial is looking for patients with liver cirrhosis to help test a new imaging method using Ga-PSMA PET/MRI. Participants will have their liver health assessed in a noninvasive way to see how well this method works.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with liver cirrhosis.
You may not be able to join if
- I have a contraindication to PET.
- I have a contraindication to MRI.
- I have an allergy to gadolinium.
- I am pregnant.
- I am breastfeeding.
- I have had too much radiation exposure in the past 12 months.
- I weigh more than 300 lbs.
- My BMI is over 33.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
A total of fifty-five (55) patients with liver cirrhosis will be enrolled in this study to produce and validate dedicated Ga-PSMA-PET/MRI acquisition protocols.
The specific hypotheses include:
* Ga-PSMA PET/MRI may allow robust and reproducible noninvasive in vivo quantitation of hepatic macro and microhemodynamics in cirrhotic patients
* Dedicated simultaneously acquired DWI sequences might qu…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Liver cirrhosis as diagnosed by imaging and/or clinical data, including pathology
Exclusion Criteria:
* Any contraindication to PET, as in attached screening form
* Any contraindication to MRI, as in attached screening form
* Any contraindication to gadolinium-based contrast…
Contacts