M. Avium WGS During Mav-PD Treatment
Recruiting
Observational Study
Mycobacterium Avium
Mycobacterium Infections, Nontuberculous
Mycobacterium Infections
Nontuberculous Mycobacterial Lung Disease
Respiratory Tract Diseases
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 40 (estimated)
- Sponsor
- University Health Network, Toronto · Other
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About This Trial
This is a prospective observational study using whole genome sequencing (WGS) to investigate whether new strains (other than the initially identified strain(s)) of M. avium are responsible for persistently culture positive sputum during treatment (refractory disease), or the reversion to culture positive sputum after prior conversion to negative. The study will further investigate for differences …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18 and older
* Willing to provide informed consent and participate in study procedures
* Residing continuously in Ontario during the past five years
* Mav-PD, either initial or recurrent (previously treated patients will be eligible) five years
* Meet American Thoracic Soc…
Contacts