Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder

Recruiting Phase 4 Interventional Study
Alcohol Use Disorder
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
21 – 65
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Basic Science
Participants needed
48 (estimated)
Sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · NIH
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About This Trial
Background: Chronic heavy drinking can cause alcohol use disorder (AUD). AUD changes how the brain works. People with AUD may drink compulsively or feel like they cannot control their alcohol use. Acamprosate is an FDA-approved drug that reduces anxiety and craving in some, but not all, people with AUD. Objective: To learn more about how acamprosate affects brain function in people with AUD. E…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: 1. Age 21-65. In younger participants, the central nervous system has not sufficiently developed, whereas in older participants, degenerative changes may confound the …
Contacts

Beth A Lee, R.N.

(301) 451-6964

beth.lee@nih.gov

CONTACT

Nancy Diazgranados, M.D.

(301) 496-7515

nancy.diazgranados@nih.gov

CONTACT