No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
400 (estimated)
Sponsor
BostonGene · Industry
Who this trial is looking for
This trial is looking for patients with certain types of advanced cancer. By participating, you will undergo genomic testing to help guide your treatment decisions.
Are You a Good Fit for This Trial?
You may be able to join if
I have breast cancer that cannot be surgically removed.
I have non-small cell lung cancer that cannot be surgically removed.
I have melanoma that cannot be surgically removed.
I have sarcoma that is advanced or metastatic.
My doctor says I have a life expectancy of more than 3 months.
I live in the United States.
I am willing to provide consent for participation.
I agree to undergo genomic and molecular profiling.
You may not be able to join if
I do not meet the inclusion criteria.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment deci…
The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment decisions and patient outcomes. This study seeks to demonstrate the clinical utility of genomic testing in guiding therapy for advanced cancer patients in community settings.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Patients must have a confirmed malignancy of:
Locally recurrent, unresectable, or metastatic breast cancer or; Unresectable stage III or metastatic non-small cell lung cancer or; Unresectable or metastatic melanoma or; Locally advanced or metastatic l sarcoma.
* Life expecta…
Inclusion Criteria:
* Patients must have a confirmed malignancy of:
Locally recurrent, unresectable, or metastatic breast cancer or; Unresectable stage III or metastatic non-small cell lung cancer or; Unresectable or metastatic melanoma or; Locally advanced or metastatic l sarcoma.
* Life expectancy \> 3 months as per the treating physician
* Willingness to provide informed consent
* Living in the United States at time of enrollment
* Agree to participate in genomic and molecular profiling
Exclusion Criteria:
* not meeting the inclusion criteria
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