Vabb After Neoadjuvant Therapy to Avoid Surgery-pCR to Avoid Breast Surgery
Recruiting
N/A
Interventional Study
Breast Cancer
Triple Negative Breast Cancer
HER2-positive Breast Cancer
Neoadjuvant Chemotherapy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 77 (estimated)
- Sponsor
- European Institute of Oncology · Other
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About This Trial
This single arm study aims to evaluate the efficacy and safety of a non-surgical approach, consisting of radiotherapy (RT) alone, for patients who have achieved a complete pathological response (pCR) following neoadjuvant chemotherapy (NACT). The study design involves the histological confirmation of pCR using vacuum-assisted biopsy (VABB) or vacuum-assisted excision (VAE) guided by ultrasound. Th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* age\> 18 years
* infiltrating breast carcinoma, non-special histotype, triple negative or HER2 +, T1-T2 N0
* single lesion
* neo-adjuvant chemotherapy treatment for at least 12 weeks according to clinical practice
* conservative surgery proposal
* M0
* tumour bed identified by…
Contacts