Liposomal Bupivacaine Use in Alveolar Bone Graft Patients

Recruiting Phase 3 Interventional Study
Cleft Lip and Palate
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
6 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Supportive Care
Participants needed
60 (estimated)
Sponsor
Kerry O'Rourke · Other
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About This Trial
The goal of this clinical trial is to learn if a pain medication called liposomal bupivacaine (brand name EXPAREL®) with epinephrine will provide better pain control, increased activity, and reduced use of opioids compared with the standard treatment for patients age 6 years and older with cleft lip and palate who have had an alveolar bone graft surgery. Investigators will look at: * pain scores …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients that are 6 and older who have a diagnosis of cleft lip and/or palate with a scheduled surgery that involves an alveolar bone graft. Exclusion Criteria: * Patients under age 6 are excluded from this study as EXPAREL® is not FDA approved for this group. * Patients wit…
Contacts

Chad A. Purnell, MD

(724)-433-1645

cpurnell@shrinenet.org

CONTACT

Benjamin M. Smith, MS

(773) 385-5865

BenjaminM.Smith@shrinenet.org

CONTACT