Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis

Recruiting N/A Interventional Study
Cystic Fibrosis in Children
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
2 – 18
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Oslo University Hospital · Other
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About This Trial
The aim of the present study is to investigate the effect of probiotic supplementation on GI related quality of life, through a randomised placebo-controlled clinical trial. Moreover, the invetigators wish to study CF microbiota and intestinal inflammation in the setting of probiotic supplementation and newly started treatment with a highly effective CF-specific treatment, elexacaftor-tezacaftor-i…
Trial Locations
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Eligibility Criteria
Inclusion criteria for WP1: * CFTR mutations eligible for treatment with ETI * Age 2-18 years. Majority of patients will be 2-6 years of age as ETI was approved from 6 years of age in 2022, and will be available for children above 2 years from 2024. * Included in the Norwegian CF Register and conse…
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