Immunomonitoring of Mold Invasive Infections

Recruiting Observational Study
Invasive Fungal Disease Mold Invasive Fungal Infection: Aspergillus, Mucorales, Fusarium, Scedosporium
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
20 (estimated)
Sponsor
Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
Mold invasive infections are associated with an important mortality despite optimization of the antifungal treatment. In a few case reports, immune checkpoints inhibitors, initially developed for neoplastic diseases, have shown a potential beneficial effect in such devastating infections by restoring an efficient immune response. The investigators propose a longitudinal monitoring of the adaptativ…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Mold invasive fungal infection: Aspergillus, Mucorales, Fusarium, Scedosporium * Proven or probable according to 2019 EORTC/MGS criteria modified by the adjunction of diabetes mellitus in the host criteria and Mucorales PCR in the microbiological criteria * Wi…
Contacts

Alexandra SERRIS, MD, PhD

06 68 80 24 92

alexandra.serris@aphp.fr

CONTACT

Gael PLASTOW, Project advisor

01 44 38 18 57

gael.plastow@aphp.fr

CONTACT