Opportunistic Salpingectomy to Prevent Ovarian Cancer
A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
Recruiting
N/AInterventional Study
Surgery
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
45 and older
Sex
Female
Study type
Interventional
Purpose
Prevention
Participants needed
266 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Other
Who this trial is looking for
This trial is looking for women aged 45 and older who are interested in a preventive surgery after watching an educational video. Participants will answer questions in the clinic before and after watching the video.
Are You a Good Fit for This Trial?
You may be able to join if
I am a woman or was assigned female at birth.
I am 45 years old or older.
I have at least one in situ fallopian tube.
I do not plan to have children in the future.
I have an average risk of developing ovarian cancer.
I have a scheduled visit with a surgeon.
I am scheduled for certain types of surgery.
I have signed the informed consent.
You may not be able to join if
I am not fluent in English or Spanish.
I have a personal history of any gynecologic cancer.
I have a hereditary breast or ovarian cancer gene.
I have suspicious lesions on imaging.
I have previously had my fallopian tubes or ovaries removed.
I am currently pregnant.
I need an emergency surgery.
I have significant pelvic fibrosis or adhesions.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to find out how many participants are interested in a surgical preventive procedure after watching an educational video. Before and after watching the video, participants will complete questionnaires in the clinic.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
Part I
* Age ≥45 years
* Scheduled visit with a nongynecologic surgeon
* Female or assigned female at birth
Part II
* Age ≥45 years
* At least one in situ fallopian tube
* No desire or plan to have children in the future
* Average risk of developing ovarian cancer
° Note: …
Inclusion Criteria:
Part I
* Age ≥45 years
* Scheduled visit with a nongynecologic surgeon
* Female or assigned female at birth
Part II
* Age ≥45 years
* At least one in situ fallopian tube
* No desire or plan to have children in the future
* Average risk of developing ovarian cancer
° Note: Average risk patients are defined as patients with no known genetic risk factor for developing ovarian cancer. Patients who, after obtaining family history, are suspected to have a hereditary ovarian cancer syndrome but have not yet been tested, will be referred for genetic evaluation.
* Planned nongynecologic, intraabdominal, or pelvic surgery
* Deemed to be a suitable candidate by gynecologic surgeon and primary nongynecologic surgeon (for example, on the basis of surgical history and current malignancy status)
* Approved and signed informed consent
Exclusion Criteria:
Part I
* Not fluent in English or Spanish
° If there is a non-english or non-spanish speaking participant who is a strong candidate and meets all other criteria for Part 2, they are able to go directly onto Part 2 without completing Part 1. (Please see additional details in section 4.1 and 7.0.)
* Known inherited ovarian cancer susceptibility
Part II
* Personal history of a gynecologic malignancy
* Carrier of a hereditary breast or ovarian cancer variant (e.g., BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D, MLH1, MSH2, MSH6, PMS2)
* Suspicious ovarian, fallopian tube, or uterine lesion on preoperative imaging
* Previous bilateral salpingectomy or bilateral salpingo-oophorectomy
* Presence of ESSURE, or other tubal-implanted birth control at the time of surgery
* Current pregnancy
* Emergent procedure or emergency procedure that has to be completed within 24 hours where clinical consent occurs in the inpatient setting or where the patient's immediate well-being is in danger or condition may be life threatening
* Primary surgeon anticipates that OS will add significant time (\>30-40min) to the planned procedure.
* Inability to access the pelvis (ex., patient prone/lateral position) during the planned procedure.
* Known history of pelvic fibrosis or significant adhesions.
* Procedures with palliative intent only
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