CPAP Treatment for Severe Uncontrolled Asthma

Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial

Recruiting N/A Interventional Study
Obstructive Sleep Apnea Asthma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
138 (estimated)
Sponsor
Hospital Clinic of Barcelona · Other
Who this trial is looking for

This trial is looking for adults with severe uncontrolled asthma and sleep apnea. Participants will receive CPAP treatment to see how it helps manage their asthma.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am over 18 years old.
  • I have severe uncontrolled asthma without recent hospitalizations.
  • I have a sleep apnea rate of 15 or more events per hour.
  • I scored 10 or less on the Epworth Sleepiness Scale.
  • I will provide informed consent.

You may not be able to join if

  • I have previously been treated with CPAP.
  • I have central sleep apnea or Cheyne-Stokes respiration.
  • I have other sleep disorders like narcolepsy.
  • I have resistant hypertension.
  • I currently smoke.
  • I have unstable health conditions that affect my asthma.
  • I am pregnant.
  • I have a condition that reduces my life expectancy to less than 1 year.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \>18 years * Diagnosis of severe uncontrolled asthma according to the criteria of the Spanish Asthma Management Guide (GEMA) or the Global Initiative for Asthma (GINA) and no hospitalizations the month prior to inclusion in the study. * Apnea hypopnea rate greater than or …
Contacts

Mireia Dalmases, MD

+34932275746

mdalmase@clinic.cat

CONTACT