No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
40 – 80
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
99 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for veterans who have had a stroke at least 6 months ago and want to improve their health through weight loss and exercise. Participants will take part in a 15-week lifestyle management program.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with a stroke at least 6 months ago.
My BMI is over 30.
I have some weakness in my legs.
I can follow instructions and communicate about my condition.
I can provide informed consent.
You may not be able to join if
I cannot walk at least 150 feet.
I have unstable heart conditions.
I have dementia.
My life expectancy is less than 1 year.
I had a blood clot or lung embolism in the last 6 months.
I have uncontrolled diabetes.
I have severe high blood pressure.
I am currently in a rehabilitation trial.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determi…
Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determine if it can effectively improve some of the physical and psychosocial problems common in Veterans who have had a stroke.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* A diagnosis of stroke at least 6 months prior
* BMI \> 30 kg/m2
* Residual paresis in the lower extremity (Fugl-Meyer LE motor score \<34)
* Ability to follow instructions, complete training and testing and to communicate exertion, pain and distress
* Provision of informed con…
Inclusion Criteria:
* A diagnosis of stroke at least 6 months prior
* BMI \> 30 kg/m2
* Residual paresis in the lower extremity (Fugl-Meyer LE motor score \<34)
* Ability to follow instructions, complete training and testing and to communicate exertion, pain and distress
* Provision of informed consent
* Individuals who meet inclusion criteria must complete an exercise tolerance test and be cleared for participation by the study cardiologist
Exclusion Criteria:
* Unable to ambulate at least 150 feet or experienced intermittent claudication while walking
* Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's
* Dementia
* Life expectancy \<1 yr
* History of DVT or pulmonary embolism within 6 months
* Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions
* Severe hypertension with systolic \>200 mmHg and diastolic \>110 mmHg at rest
* Current enrollment in a rehabilitation trial to enhance motor or psychosocial recovery
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