GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac Surgery

Recruiting Phase 4 Interventional Study
Myocardial Injury
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Prevention
Participants needed
372 (estimated)
Sponsor
The University of Hong Kong · Other
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About This Trial
This is an investigator initiated, multi-center, open-labelled, superiority randomized controlled trial of 372 patients undergoing elective non-cardiac surgery. Recruited patients will be randomized in a 2:1 ratio to receive single subcutaneous dose of Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RAs) 1 to 14 days prior to surgery or receive routine care. Dulaglutide (Trulicity; Eli Lilly, USA…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Planned elective intermediate to high risk non-cardiac surgery * Anticipated to remain hospitalized for at least one night after surgery * Voluntarily agrees to participate by providing written informed consent Exclusion Criteria: * History of symptomatic hy…
Contacts

Chun Ka Wong, Clinical Assistant Professor

+852 2255 3597

wongeck@hku.hk

CONTACT

Lily Hung, Master

+852 2255 4169

nga98@hku.hk

CONTACT