New Methods to Detect Delirium in Dementia Patients
Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department
Recruiting
Observational Study
DeliriumDementiaHospital Acquired Condition
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
65 and older
Sex
Any
Study type
Observational
Participants needed
60 (estimated)
Sponsor
Ohio State University · Other
Who this trial is looking for
This trial is looking for older adults with dementia who are visiting the emergency department. It involves using special wrist sensors to help identify delirium more accurately than current methods.
Are You a Good Fit for This Trial?
You may be able to join if
I am 65 years old or older
I have a known diagnosis of dementia or it is suspected
I expect to stay in the emergency department or hospital for more than 4 hours
You may not be able to join if
I am currently intubated or on mechanical ventilation
I am undergoing a procedure that requires sedation
I cannot consent due to cognitive impairment and don't have a caregiver present
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Delirium is highly prevalent and very bad for patients with dementia. Delirium is a dangerous medical condition that occurs in 6-38% of older Emergency Department patients and 70% of ICU patients. A person who develops delirium in the ED or hospital has a 12 times higher odds of being newly diagnosed with dementia in the next year compared to a similar patient who does not become delirious. Deliri…
Delirium is highly prevalent and very bad for patients with dementia. Delirium is a dangerous medical condition that occurs in 6-38% of older Emergency Department patients and 70% of ICU patients. A person who develops delirium in the ED or hospital has a 12 times higher odds of being newly diagnosed with dementia in the next year compared to a similar patient who does not become delirious. Delirium is especially dangerous for persons living with Alzheimer Disease and Related Dementias (AD/ADRD). Persons living with ADRD have an almost 50% chance of developing delirium in the hospital.
Clinicians are bad at recognizing delirium. A recent systematic review led by the Geriatric Emergency Care Applied Research network (NIH funded) found that current delirium screening tools are at most 64% sensitive, meaning that physicians can identify some phenotypes of delirium well, but cannot easily rule out delirium in acutely ill older patients.
The investigators propose integrating wrist biosensors into the emergency management of older adults with dementia. The investigators will monitor heart rate variability, movement, and electrodermal activity (electrical activity of at the level of the skin) to determine if an array of biosensors more sensitive to delirium than current verbal screening tools.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* adults patients 65+ years old with a known diagnosis of dementia or medical team highly suspects or confirms dementia this visit.
* Emergency Department visit and/or hospitalization anticipated to last \>4 more hours from the time of enrollment.
Exclusion Criteria:
* Intubat…
Inclusion Criteria:
* adults patients 65+ years old with a known diagnosis of dementia or medical team highly suspects or confirms dementia this visit.
* Emergency Department visit and/or hospitalization anticipated to last \>4 more hours from the time of enrollment.
Exclusion Criteria:
* Intubation/mechanical ventilation
* Patients undergoing a procedure requiring sedation
* Patients who cannot consent due to cognitive impairment and do not have a legally authorized representative or caregiver present.
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