A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia
Recruiting
Phase 4
Interventional Study
Hypotension Drug-Induced
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 180 (estimated)
- Sponsor
- Dalian Municipal Central Hospital · Other
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About This Trial
The purpose of this study is to investigate whether norepinephrine(N), phenylephrine(P) or ephedrine(E) have different effect on cerebral oxygenation in abdominal surgery with propofol or sevoflurane.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* ASA I-III, age 18-80 years
* Elective abdominal surgery
* Signed informed consent
Exclusion Criteria:
* ASA≥IV
* Preoperative unstable blood hemodynamics
* Allergy to ephedrine, phenylephrine or norepinephrine
* Decrease in MAP \<20%
* Severe cardiovascular disorder
Contacts