An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

Recruiting Observational Study
Hepatocellular Carcinoma Intrahepatic Cholangiocarcinoma Cholangiocarcinoma Primary Liver Cancer Primary Liver Carcinoma Hepatic Cancer Hepatic Carcinoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
400 (estimated)
Sponsor
City of Hope Medical Center · Other
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About This Trial

It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate these two cancers before surgery.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * A histologically confirmed diagnosis of hepatocellular carcinoma * A histologically confirmed diagnosis of intrahepatic cholangiocarcinoma * Received standard diagnostic and staging procedures as per local guidelines * Availability of at least one blood-derived sample, drawn b…
Contacts

Ajay Goel, PhD

6262183452

AJGOEL@COH.ORG

CONTACT