Blood Test for Early Detection of Colorectal Cancer
Early Detection of Advanced Adenomas and Colorectal Cancer
Recruiting
Observational Study
Colorectal CancerColorectal NeoplasmsColorectal PolypColorectal AdenocarcinomaColorectal DisordersColorectal DysplasiaColorectal Cancer Stage IColorectal Cancer Stage IIColorectal Cancer Stage IIIColorectal Cancer Stage IVColorectal Neoplasms MalignantColorectal Serrated AdenocarcinomaColorectal Adenoma With Severe DysplasiaColorectal Adenoma With Mild DysplasiaColorectal Adenoma With Moderate DysplasiaColorectal Adenoma and Carcinoma 1Colorectal Adenomatous PolypColorectal Adenocarcinoma Metastatic in the Liver
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
2,000 (estimated)
Sponsor
City of Hope Medical Center · Other
Who this trial is looking for
This trial is looking for people who have had a colonoscopy and a blood test. Participants will help develop a new blood test to find colorectal cancer and polyps earlier.
Are You a Good Fit for This Trial?
You may be able to join if
I have had a colonoscopy when my blood was sampled.
I have had diagnostic procedures as per local guidelines.
I had at least one blood sample taken before any treatment.
I received a standard diagnosis for my condition.
You may not be able to join if
I have hereditary colorectal cancer syndromes.
I have inflammatory bowel diseases.
I have not provided written informed consent.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* All individuals included in the study need to have had a colonoscopy at the time of blood sampling.
* Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
*…
Inclusion Criteria:
* All individuals included in the study need to have had a colonoscopy at the time of blood sampling.
* Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
* Received standard pathological and endoscopic diagnosis and assessment for cohort assignment.
Exclusion Criteria:
* Hereditary colorectal cancer syndromes (identified through genetic testing).
* Inflammatory bowel diseases.
* Lack of written informed consent.
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