DEB-TACE Prior to Liver Transplantation in the Treatment of HCC

Inclusion Criteria: 1. Age 18-75 years; 2. Subjects with viral hepatitis or cirrhosis are clinically diagnosed according to AASLD standards, which require a history of viral hepatitis or cirrhosis combined with imaging examinations (enhanced CT, MRI, second-generation ultrasound contrast agents). When the tumor diameter is greater than 2 cm, a diagnosis can be made if one imaging technique shows typical arterial phase rapid enhancement and rapid washout. If the diameter is 1-2 cm, two imaging techniques must confirm this, or one imaging technique confirms it and alpha-fetoprotein (AFP) is greater than 400 ng/ml. For subjects who cannot be clinically diagnosed, histological or cytological biopsy confirmation is required; original biopsy records can also be used for diagnosis. 3. Child-Pugh score A-B grade; 4. Tumor present in the right lobe of the liver; 5. Liver cancer assessment meeting the "up to seven" criteria: the sum of tumor size and number does not exceed 7; 6. ECOG-PS score 0-1; 7. Scheduled for living donor liver transplantation as the primary treatment; 8. Signed informed consent form. Exclusion Criteria: 1. Presence of definite cancer thrombi in the main portal vein, vena cava, or main bile duct; 2. Severe hepatic encephalopathy; 3. Coexisting pulmonary arterial hypertension (moderate to high risk, WHO Grade III-IV); 4. Severe contrast agent allergy; 5. Irreversible hepatic artery to hepatic vein shunt; 6. Special types of anatomical variations (Asan portal vein type III); 7. Extrahepatic metastatic tumors; 8. Concurrent active hepatitis or severe infection; 9. Tumor dissemination or distant metastasis, expected survival \<3 months; 10. Renal dysfunction, creatinine \>176.8 umol/L or creatinine clearance rate \<30ml/min; 11. White blood cell count \<3.0x109/L, platelet count \<50x106/L, and unable to correct; 12. Inability to tolerate surgical anesthesia (severe infection, cardiopulmonary insufficiency, cerebrovascular disease); 13. Severe psychiatric illness; 14. Other reasons deemed unsuitable for participation by the investigator.