Genetic Architecture of Acute Aortic Syndromes and Aortic Aneurysm.
Recruiting
Observational Study
Acute Aortic Dissection
Thoracic Aortic Aneurysm
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 730 (estimated)
- Sponsor
- University Hospital, Basel, Switzerland · Other
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About This Trial
The aim of this study is to explore the genetic information associated with the development of TAA and aAD in individuals without history or syndromic features (Marfan syndrome, Ehlers-Danlos syndrome, Turner syndrome etc.) for aortic disease. For this purpose, whole genome sequencing will be performed in patients with documented aortic aneurysm or/and aortic dissection.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* All adult patients \> 18 years who underwent surgery for aAD or TAA intervention at the University Hospital Basel, starting in 2015.
* All patients who will undergo surgery for aAD or TAA at the University Hospital Basel, beginning in 2024.
Exclusion Criteria:
* Patients wil…
Contacts