Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies
Recruiting
N/A
Interventional Study
Upper Abdominal Malignancies
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Health Services Research
- Participants needed
- 17 (estimated)
- Sponsor
- University of Pittsburgh · Other
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About This Trial
Standard planning constraints for liver SBRT incorporate strict dose-volume limits for normal liver parenchyma to minimize the risk of radiation-induced liver disease. The presence of diurnal and fasting/fed variations in liver volume therefore carry substantial potential for introducing errors into estimates of dose-volume distribution within normal liver tissue, as well as affecting day-to-day s…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
• Have primary upper abdominal (pancreatic, bile duct, liver) cancer or upper abdominal metastases (liver, adrenal, upper abdominal lymph nodes) planned to undergo SBRT.
Exclusion Criteria:
* Had prior Radiation Therapy to the liver
* Contraindication to receipt of iodinated I…
Contacts