Wharton's Jelly Injections for Low Back Pain

Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain

Recruiting Phase 1 Interventional Study
Low Back Pain
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
20 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
100 (estimated)
Sponsor
R3 Stem Cell · Industry
Who this trial is looking for

This trial is looking for adults over 20 with chronic low back pain. Participants will receive injections of Wharton's Jelly to see if it helps relieve their pain.

Are You a Good Fit for This Trial?
Must not be taking NSAIDs
Rules you out Organ transplantationRheumatoid arthritisAutoimmune disorders

You may be able to join if

  • I am over age 20.
  • I have chronic low back pain.
  • My BMI is less than 50.
  • I have a pain score of 4 or higher.
  • I can provide written consent in English.
  • I can follow study requirements and attend visits.
  • If female, I am abstinent, sterilized, or postmenopausal.

You may not be able to join if

  • I have taken pain medications in the past 2 weeks.
  • I have had any lumbar injections in the past 6 months.
  • I have had lumbar spine surgery in the past 6 months.
  • I have had a traumatic injury to my lumbar spine in the past 3 months.
  • I am breastfeeding, pregnant, or planning to get pregnant during the study.
  • I have a history of serious autoimmune disorders.
  • I have a diagnosis of cancer in the past 5 years.
  • I have a lumbar infection or used antibiotics for it in the past 3 months.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: • Patient must * Be over age 20. * Suffering from chronic lumbar pain * Body Mass Index (BMI) \<50 Kilograms/m2. * Pain score of 4 or more on the Numeric Pain Rating Scale (NPRS). * Female participants must be abstinent, surgically sterilized or postmenopausal. * Premenopausal …
Contacts

David L Greene, MD, PhD, MBA

(602) 677-8981

dgreene@r3medicalresearch.com

CONTACT

Katherine Minter-Dykhouse, PhD

4803066256

kmd@bello.bio

CONTACT