Pilot Study of the Human Metagenome in Metabolic Diseases
Recruiting
Observational Study
Obesity
Sarcopenia
Sarcopenic Obesity
Chronic Inflammation
Metabolic Syndrome
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 21 – 99
- Sex
- Any
- Study type
- Observational
- Participants needed
- 600 (estimated)
- Sponsor
- Sengkang General Hospital · Other
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About This Trial
This is a cohort study to understand the role of the human metagenome, and associated metabolites, in health and in various diseased states, in particular obesity as well as sarcopenia.
Recruited participants will have their fecal, salivary, urine, serum, and in certain instances, mucosal samples taken, for metagenomic sequencing and metabolite testing.
We hope to uncover various differences and…
Trial Locations
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Eligibility Criteria
Inclusion Criteria (obese cohort):
* Obese (BMI\>27.5kg/m2)
Inclusion Criteria (sarcopenic cohort):
* Sarcopenic patients, defined as 1) low handgrip strength (\<26 for males; \<18kg for females), AND/OR low gait speed (\<0.8m/s) AND low muscle mass (\<7.0kg/m2 for males; \<5.7kg/m2 for females)
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Contacts