Mechanism Study of Ventilator-Induced Lung Injury in Elderly People.
Recruiting
Observational Study
Ventilator-Induced Lung Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Sex
- Any
- Study type
- Observational
- Participants needed
- 1,000 (estimated)
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Other
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About This Trial
1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age. 2. We collect peripheral blood from patients with different ages and duration of mechanical ventilation to explore the correlation between the degree of endothelial/epithelial damage, age and duration of mechanical ventilation.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Lung tissues from patients with different ages:
Patients undergoing elective general anesthesia surgery; Patients undergoing partial lung resection with mechanical ventilation; American Society of Anesthesiology (ASA) grade 2-3;
2. Peripheral blood from patients with diff…
Contacts