Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints

Recruiting Observational Study
Osteoarthritis Thumb Osteoarthritis, Knee Metabolic Disease
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
25 and older
Sex
Any
Study type
Observational
Participants needed
120 (estimated)
Sponsor
Region Skane · Other
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About This Trial
The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints. The degradation of extracellular matrix (ECM) proteins in thumb basal joints will be evaluated in association to the metabolic profile of the patient, but we also aim to compare the ECM degradation and inflammatory profiles with articular cartilage degradati…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Men and women age ≥ 25 years * Radiologically confirmed and symptomatic thumb basal joint osteoarthritis (OA) planned for trapeziectomy Exclusion Criteria: * Previous surgery to the affected thumb basal joint * Post-traumatic thumb basal joint OA * Rheumatoid arthritis or ot…
Contacts

Elisabeth Brogren, MD, PhD

+46 40331723

elisabeth.brogren@med.lu.se

CONTACT

My von Walter, MD

CONTACT