Oxygen Levels for Preterm Infants with Lung Issues
Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
Recruiting
N/A
Interventional Study
Bronchopulmonary Dysplasia
Pulmonary Hypertension
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 1 Month – 5 Months
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 39 (estimated)
- Sponsor
- University of Alabama at Birmingham · Other
Who this trial is looking for
This trial is looking for infants born very preterm who have a lung condition called pulmonary hypertension. Taking part may involve receiving different amounts of supplemental oxygen to see if it helps improve their health.
Are You a Good Fit for This Trial?
You may be able to join if
- I was born between 22 and 31 weeks of pregnancy
- I have been diagnosed with pulmonary hypertension
- I am receiving supplemental oxygen
- I have mature retinas
You may not be able to join if
- I have major congenital anomalies
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmonary hypertension of which 50% of children will die before the age of 2. Physicians are currently limited in their ability to select the most appropriate oxygen targets that will improve outcomes in infants with this condition. This clinical t…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Between 22w 0/7d and 31w 6/7d gestation at birth
* Diagnosed with echocardiographic pulmonary hypertension (1) \>20% flow of blood across the PDA from the pulmonary to arterial circulation, (2) end-systolic flattening of the interventricular septum (eccentricity index \>1.3), …
Contacts