Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics

Recruiting N/A Interventional Study
Thiazide Associated Hyponatremia
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
136 (estimated)
Sponsor
University Hospital, Basel, Switzerland · Other
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About This Trial

This study is looking at two new parameters, aSID and ChU, to see if these can help physicians to distinguish between different causes of low sodium levels (hyponatremia) in Patients taking a medicament against high blood pressure (thiazide). Researchers also want to see if using these new parameters to decide on treatment works just as well, or better, than the current standard treatments.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Hospitalized patients presenting at University Hospital Basel * aged 18 years or older * able to give informed consent as documented by signature * with serum sodium level \< 133 mmol/l and serum osmolality \< 300 mOsm/kg * with treatment with thiazide or thiazide-like diureti…
Contacts

Laura Potasso, Dr. med. sc.

+41 61 328 58 76

laura.potasso@usb.ch

CONTACT