A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma.
Recruiting
Phase 1
Interventional Study
Hodgkin Lymphoma
Non Hodgkin Lymphoma
At a Glance
- Age
- 6 – 25
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 10 (estimated)
- Sponsor
- Murdoch Childrens Research Institute · Other
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About This Trial
PEGASUS aims to test acceptability and feasibility of studying phenoconversion (the change in metabolism phenotype) using probe medications in a paediatric oncology patient population. The study will be conducted in patients (6-25 years of age) with Hodgkin lymphoma or non-Hodgkin lymphoma as exemplar cohort, but with the understanding that cancer-directed and supportive care medicines of the CYP3…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 6-25 years of age.
* New diagnosis of Hodgkin Lymphoma or Non-Hodgkin Lymphoma.
* Able to swallow and absorb oral or nasogastric tube (NGT) administration of probe drugs.
* Able to provide written informed consent.
Exclusion Criteria:
* Failure to comply with inclusion c…
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