GPC3 Imaging for Liver Cancer Diagnosis
Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma
Recruiting
Early Phase 1
Interventional Study
Malignant Neoplasm of Liver
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 100 (estimated)
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Other
Who this trial is looking for
This trial is looking for adults with liver cancer or healthy volunteers. Participants will undergo special imaging tests to help diagnose and understand liver cancer better.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old
- I have been diagnosed with liver cancer or I am a healthy volunteer
- I am willing to sign the consent form
- I can follow the visit and treatment schedule
- I have a history of liver cancer that has come back after treatment
You may not be able to join if
- I am pregnant or breastfeeding
- I cannot sign the consent form
- I have serious system diseases or electrolyte issues
- I am allergic to imaging agents used in the study
- My blood sugar is higher than 11.0 mmol/L before the test
- I cannot complete the imaging tests
- I have poor compliance or other factors that may interfere with the study
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
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Answer a few quick questions to see if you may meet the eligibility requirements.
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About This Trial
This is a diagnostic study. Patients were recruited from patients with clinically suspected or confirmed hepatocellular carcinoma and healthy volunteers were recruited for PET/or PET/CT imaging targeting a GPC3-specific probe (in the case of 68Ga-NOTA-aGPC3-scFv) , to observe the reaction of volunteers and patients after injection of drugs, to evaluate the pharmacokinetics in vivo and the efficacy…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 1: Voluntarily participate and the person or their legal representative can sign an informed consent form
* 2: Adult patients (18 years of age or older), regardless of gender
* 3: Patients with newly diagnosed hepatocellular carcinoma with high clinical suspicion or confirmati…
Contacts