Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

Recruiting Phase 2 Interventional Study
Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Indolent B-Cell Non-Hodgkin Lymphoma Refractory Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Indolent Non-Hodgkin Lymphoma Refractory Indolent Non-Hodgkin Lymphoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
112 (estimated)
Sponsor
Mayo Clinic · Other
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About This Trial
This phase II trial compares the safety, side effects and effectiveness of reduced dose radiation therapy to standard of care dose radiation in treating patients with indolent non-Hodgkin lymphoma. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Standard of care radiation treatment for indolent non-Hodgkin lymphoma is usually deliv…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Histological confirmation of indolent B-cell lymphoma that can include any of the following: * Follicular lymphoma (grade 1 or 2 or 3A) * Marginal zone lymphoma (nodal or extranodal) * Follicle center lymphoma * Any stage disease * Initial, refractory, …
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