Effect of Esketamine on Conscious State in Patients With pDoC
Recruiting
N/A
Interventional Study
Esketamine
Consciousness Disorders
At a Glance
- Age
- 16 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 116 (estimated)
- Sponsor
- Beijing Tiantan Hospital · Other
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About This Trial
The goal of this clinical trial is to learn about the effect of intraoperative infusion of subanesthetic dose of esketamine on conscious status in patients with prolonged disorders of consciousness under sevoflurane anesthesia.
Participants will be patients with prolonged disorders of consciousness undergoing surgery with general anesthesia at Beijing Tiantan Hospital. 0.3mg/kg esketamine or sali…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1.16-65 years old 2.Native Chinese language 3.pDoC after acquired brain injury 4.Scheduled to undergo surgery 5.Signed informed consent
Exclusion Criteria:
1. Continuous sedation treatment was carried out within 72 hours before the study
2. Airway stenosis and severe ventilati…
Contacts