In this trial, we proposed an individualized acute normovolemic hemodilution (ANH), and conduct a randomized controlled trial to testify the effect of individualized ANH on red cells requirement for non-cardiac surgeries with anticipating major blood loss in adults.
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Eligibility Criteria
Inclusion Criteria:
* Patients undergoing elective non-cardiac surgery with an anticipated red blood cells transfusion \>8 units (or 1600ml)
* Aged 18\~75 years
* Preoperative Hb level \> 120g/L for men and \> 110g/L for women.
Exclusion Criteria:
* Refusal of blood transfusion
* Cardiopulmonary …
Inclusion Criteria:
* Patients undergoing elective non-cardiac surgery with an anticipated red blood cells transfusion \>8 units (or 1600ml)
* Aged 18\~75 years
* Preoperative Hb level \> 120g/L for men and \> 110g/L for women.
Exclusion Criteria:
* Refusal of blood transfusion
* Cardiopulmonary insufficiency
* Cerebrovascular disease
* Renal impairment
* Hemoglobinopathies or blood system diseases
* Other situations not suitable for inclusion in clinical trial.
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