Can Patients With Atrial Fibrillation Safely Discontinue Anticoagulant Therapy After Cardiac Surgery? (ATLAAC)

Recruiting Phase 4 Interventional Study
Atrial Fibrillation Left Atrial Appendage Absent Anticoagulant Adverse Reaction
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
1,220 (estimated)
Sponsor
Odense University Hospital · Other
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About This Trial
Left atrial appendage (LAA) closure has become a frequent addition to oral anticoagulation in patients with atrial fibrillation who undergo cardiac surgery. The procedure significantly reduces the risk of stroke and systemic embolism, which may render anticoagulation unnecessary or even harmful when considering the associated increased risk of bleeding. A clinical trial to address the need for ant…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \> 18 years * Previously undergone any type of cardiac surgical procedure including any type of surgical LAA closure (use of any of the following techniques; amputation and suture closure, stapler closure, non-amputating suture closure or closure with an approved surgical …
Contacts

Kristina Gosvig, M.D.

+4551520696

kristina.gosvig@rsyd.dk

CONTACT

Julie Goller, M.D.

22951855

julie.goller@outlook.com

CONTACT