Passive Stretching in Peripheral Arterial Disease Patients

Recruiting Phase 2 Interventional Study
Peripheral Arterial Disease Walking, Difficulty Inflammation
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
40 – 90
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
64 (estimated)
Sponsor
University of Wisconsin, La Crosse · Other
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About This Trial
Peripheral artery disease (PAD) leads to higher mortality rates and strains healthcare systems due to increased costs. It causes leg pain during walking due to reduced blood flow. Nitric oxide (NO) deficiency contributes to vascular issues in PAD, with few effective treatments available. Passive calf muscle stretching boosts NO levels, vascular health, and walking ability in PAD patients. However,…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Ankle-brachial index of 0.90 or less Stable condition for at least 3 months Exclusion Criteria: Habitual exercise or cardiovascular rehabilitation program during the past 3 months Critical limb ischemia, amputation, or leg pain at rest Major surgery or lower extremity revascul…
Contacts

Jacob T Caldwell, Ph.D.

608-785-8684

jcaldwell@uwlax.edu

CONTACT