Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Recruiting N/A Interventional Study
Graft-Versus-Host Disease Hematopoietic Stem Cell Transplantation Child, Only Haploidentical Hematopoietic Stem Cell Transplantation
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
8 Weeks – 18
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
110 (estimated)
Sponsor
Sijia Gu · Other
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About This Trial

This is a single-center prospective, non-randomized controlled clinical study in China using CliniMACS TCRα/β+ cell depleted stem cell haploidentical donors versus conventional Beijing protocol for haploidentical hematopoietic stem cell transplantation in children.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 8 weeks to 18 years * Children who meet the indicators haploidentical hematopoietic cell transplantation * No HLA ≥ 9/10 donor or not suitable for this type of donor due to illness * Informed consent must be signed (by the patient or legal representative) Exclusion Criter…
Contacts

Jing Chen, PhD

38626161

chenjing@scmc.com.cn

CONTACT