Exploration of Mechanisms for Weaning Failure
Recruiting
Observational Study
Weaning Failure
Central Respiratory Depression
Diaphragm Injury
Phrenic Nerve Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 30 (estimated)
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University · Other
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About This Trial
This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline physiologic parameters of the patients prior to the spontaneous breathing test（SBT).
The participants will be divided into a successful withdrawal group and a failed withdrawal …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Invasive mechanical ventilation for at least 48 hours
Exclusion Criteria:
* neuromuscular disease；Postoperative patients or patients with traumatic brain injury
Contacts