Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy

Recruiting Early Phase 1 Interventional Study
Hypertrophic Cardiomyopathy Without Obstruction
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
26 (estimated)
Sponsor
University of Pennsylvania · Other
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About This Trial
The goal of this clinical trial is to learn if sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, works to treat symptomatic, nonobstructive hypertrophic cardiomyopathy (noHCM) in adult patients. It will also learn about the safety of sotagliflozin in this patient population. The main questions it aims to answer are: 1. Will sotagliflozin be well tolerated in patients with nonobstructive HCM? 2. Wi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age at least 18 years, both sexes 2. Provision of signed and dated informed consent form 3. Stated willingness to comply with all study procedures and availability for the duration of the study 4. Ability to take oral medication and be willing to adhere to the study intervent…
Contacts

Sharlene Day, MD

734-548-0394

sharlene.day@pennmedicine.upenn.edu

CONTACT

Kim Clinton

215-431-4545

kimberly.clinton@pennmedicine.upenn.edu

CONTACT