Immediate Angioplasty For Acute Ischemic Stroke With Severe Intracranial Atherosclerotic Stenosis

Recruiting N/A Interventional Study
Stroke, Acute Ischemic
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
412 (estimated)
Sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Other
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About This Trial

A multicenter, prospective, open-label, blinded endpoint, randomized controlled trial that aims to evaluate the effect of immediate angioplasty (with or without stenting) for acute ischemic stroke (AIS) with severe intracranial atherosclerotic stenosis (ICAS) in improving the 90-day functional outcome.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Aged 18 years or older. 2. Diagnosed with AIS and baseline NIHSS ≥6. 3. Pre-stroke mRS ≤2. 4. Time from symptom onset to randomization ≤ 24 hours; the onset time refers to "Last Known Well" (LKW). 5. Non-contrast CT ASPECTS score ≥6. 6. CTA confirmed severe ICAS (70-99%) of t…
Contacts

Xinguang Yang, M.D.

86-20-81332619

yangxinguang0926@163.com

CONTACT

Xiongjun He, M.D., Ph.D.

drxjhe@163.com

CONTACT