Early Switch from Controlled to Assisted Ventilation
Recruiting
N/A
Interventional Study
Acute Hypoxemic Respiratory Failure
Mechanical Ventilation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 20 (estimated)
- Sponsor
- Erasmus Medical Center · Other
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About This Trial
The goal of this physiological intervention study is to unravel the (patho)physiological mechanisms and potential clinical benefits of a pre-specified early switch from controlled to assisted ventilation in mechanically ventilated adult patients with acute hypoxemic respiratory failure (PaO2/FiO2 ratio \< 200 mmHg).
The intervention is that participants will be switched from controlled to assiste…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18 years old
* Written informed consent from a legal representative
* Mechanical ventilation via an endotracheal tube
* Acute hypoxemic respiratory failure with PaO2/FiO2 ratio \< 200 mmHg
* Under continuous sedation with or without paralysis
Exclusion Criteria:
* Expected m…
Contacts