Effects of Nasal Ventilation on Cerebral and Pulmonary Function in Orally Intubated Patients
Recruiting
Observational Study
Hypoxemic Acute Respiratory Failure
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 22 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
The passage of air through the nasal cavity generates rhythmic oscillations transmitted by the olfactory bulb to the brain, which induces cerebral activation in functional areas and is associated with better cognitive performance compared to oral breathing. Consequently, the abolition of nasal ventilation in patients intubated via the orotracheal route could have deleterious effects on brain activ…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age ≥ 18 years old
2. Hypoxemic acute respiratory failure
3. Intubation and mechanical ventilation since less than 4 days
4. PaO2/FiO2 ratio less than 200
5. RASS\<-4
6. Consent obtained from next of kin
7. Patient with health insurance
Exclusion Criteria:
1. Central nervou…
Contacts