Relationship Between Circulating Sclerostin and Bone Lesions in Patients With Mastocytosis
Recruiting
Observational Study
Mastocytosis
Bones
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 50 (estimated)
- Sponsor
- Medical University of Lublin · Other
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About This Trial
Mastocytosis is very rare and highly heterogeneous group of disorders, characterized by the accumulation of clonal mast cells which can infiltrate several organs and tissues. Bones are the most frequent localization of systemic mastocytosis. The aim of our research was to explain the potential role of sclerostin in the pathogenesis of bone disease in mastocytosis.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age \> 18 years
* Mastocytosis defined according to WHO criteria
* Known KIT mutation status
Exclusion Criteria:
* History of organ transplant
* Inability to give informed consent
* Pregnancy, Breastfeeding
* Vulnerable Patient, defined as: patient with another uncontrolled …
Contacts