A Study of VET3-TGI in Patients With Solid Tumors

Recruiting Phase 1 Interventional Study
Solid Tumor, Adult Microsatellite Stable Colorectal Cancer Head and Neck Squamous Cell Carcinoma Cervical Cancer Kidney Cancer Renal Cell Carcinoma Melanoma Stage IV Merkel Cell Carcinoma of Skin Mesothelioma Non-small Cell Lung Cancer Cutaneous Squamous Cell Carcinoma (CSCC) Urothelial Carcinoma Bladder Squamous Cell Carcinoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
KaliVir Immunotherapeutics · Industry
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About This Trial
VET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers. VET3-TGI has not been given to human patients yet, and the current study is designed to find a safe and effective dose of VET3-TGI when administered by direct injection into tumor(s) (called an intratumoral injection) or when given intravenously (into the vein) both alone and in combination with atezolizumab in patients wit…
Trial Locations
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Eligibility Criteria
Key Inclusion Criteria: * Have pathologically confirmed, advanced, unresectable, or metastatic solid tumors. Preferred indications include, but are not limited to, breast carcinoma, bladder carcinoma, cervical squamous carcinoma, colorectal carcinoma, esophageal carcinoma, head and neck squamous ca…
Contacts

Adina Pelusio

+13057722084

clinops@kalivir.com

CONTACT

James Burke, MD

clinops@kalivir.com

CONTACT