Prognostic Markers for Sepsis and Septic Shock
Identification of Markers of Poor Clinical Prognosis in Sepsis by Epigenetic Analysis
Recruiting
Observational Study
Sepsis Syndrome
Septic Shock
Sepsis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 45 – 75
- Sex
- Male
- Study type
- Observational
- Participants needed
- 25 (estimated)
- Sponsor
- Assistance Publique Hopitaux De Marseille · Other
Who this trial is looking for
This trial is looking for male patients aged 45 to 75 who have developed bacterial sepsis after major surgery. Participants will have their epigenetic markers compared to understand the progression of sepsis.
Are You a Good Fit for This Trial?
You may be able to join if
- I am a male patient.
- I am between 45 and 75 years old.
- I have undergone major esophageal or digestive cancer surgery.
- I have post-operative gram-negative bacterial sepsis.
You may not be able to join if
- I am under 45 or over 75 years old.
- I am a female patient.
- I have had non-cancer surgeries.
- I have gram-positive bacterial or fungal infections without gram-negative bacteria.
- I have hematological cancer.
- I am immunocompromised.
- I oppose data collection and analysis for this study.
- I am under guardianship or curatorship.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Sepsis is a multifactorial syndrome characterized by a dynamic course and a clinical outcome dependent on several factors, and responsible for one in five deaths worldwide. The aim of this trial is to identify new prognostic markers for the progression of sepsis to septic shock, by comparing epigenetic markers between patients who have or have not developed severe forms of sepsis.
The main object…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male patients,
* Patients between 45 and 75 years of age,
* Patients undergoing major esophageal or digestive carcinological surgery,
* Patients with post-operative gram-negative bacterial sepsis (proven or suspected in the context of organ failure).
Exclusion Criteria:
* pa…
Contacts