The Role of Peripheral Afferents in Modulating Post-stroke Central Pain

Recruiting Phase 3 Interventional Study
Stroke
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
36 (estimated)
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France · Government
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About This Trial
Central post-stroke pain (CPP) is extremely difficult to relieve and responds very poorly to analgesics targeting neuropathic pain, probably because the mechanisms underlying this pain remain poorly understood. Stroke pain is traditionally considered to be of central origin and related to changes in the spinal cord and/or brain nociceptive systems. However, a recent study in a small cohort of pat…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients aged 18 years and over with no maximum age (blocks are generally very well tolerated in the very elderly) 2. Pain in the upper or lower limb distal enough to be completely covered by a peripheral nerve block 3. Chronic pain for at least 6 months 4. Ischaemic or haemo…
Contacts

VALERIA MARTINEZ, MD

01 47 10 76 22

valeria.martinez@aphp.fr

CONTACT

NADINE ATTAL, MD

0149095931

nadine.attal@aphp.fr

CONTACT