Senescent Endometrial Cells in Patients with Thin Endometrial Lining

Recruiting Observational Study
Asherman's Syndrome Thin Endometrial Lining Cell Senescence
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 39
Sex
Female
Study type
Observational
Participants needed
100 (estimated)
Sponsor
Trio Fertility · Other
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About This Trial
The goal of this observational study is to determine if thin endometrial lining that is unresponsive to estrogen might be associated with the presence of senescent cells in patients following long-term use of oral contraceptives. The main question it aims to answer is: Are there any senescent cells present in thin endometrial lining? During the luteal phase of the cycle, participants will will u…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 18-39 * BMI - up to 35 * Thin endometrium after OCP use * Asherman's syndrome * Women already undergoing endometrial biopsy for infertility testing (eg. EMMA testing) * Women with archived endometrial biopsy samples Exclusion Criteria: * Women with systemic disease (Rheu…
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