The Effect of Local and Systemic Tranexamic Acid on Edema and Ecchymosis in Orbital Surgery
Recruiting
Phase 4
Interventional Study
Orbital Edema
Orbital Ecchymosis
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 150 (estimated)
- Sponsor
- Montefiore Medical Center · Other
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About This Trial
Tranexamic acid (TXA) is a synthetic reversible competitive inhibitor to plasminogen lysine receptor, which prevents plasmin formation and stabilizes the fibrin matrix, thus reducing bleeding. While recent studies have demonstrated the antifibrinolytic benefits of TXA in obstetric and gynecologic conditions, traumatic hemorrhage, cardiac surgery, total knee arthroplasty, and more, there is a pauci…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients undergoing orbital surgery (decompressions, fracture repairs, enucleations, eviscerations, etc.)
* Patients who are at least 18 years of age
* Patients that have the capacity to consent
Exclusion Criteria:
* Any history of previous orbital surgery
* Any patient unde…
Contacts