Viral Infection of HSPC Impacts Hematopoiesis
Recruiting
Observational Study
HIV-1
SARS-CoV-2
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 45 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
We propose to demonstrate that HIV-1 and SARS-CoV-2 are capable of targeting long-lived HSPC with self-renewal capacities. These progenitors, thus transformed into host cells, can give rise to a durable source of infected cells with an impact on hematopoiesis.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
HIV patients :
* HIV-positive patients with a negative or positive viral load.
* managed at Ambroise Paré Hospital.
* patients with a bone marrow biopsy or myelogram performed as part of their care.
Healthy subjects without HIV - patients with a BM biopsy or myelogram performe…
Contacts