Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis
Recruiting
Observational Study
Systemic Sclerosis
Other Connective Tissue Disease
Systemic Lupus Erythematosus
Dermatomyositis
ANCA Associated Vasculitis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 260 (estimated)
- Sponsor
- CHU de Reims · Other
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About This Trial
Systemic SClerosis (SSC) is a systemic disease characterized by limited or diffuse cutaneous sclerosis, microangiopathy, overproduction of autoantibodies and variable organ damage due to vasculopathy and/or fibrosis. The loss of self-tolerance is believed to be caused by the dysregulation of both innate and adaptive immune systems and may involve Reactive Oxygen Species (ROS).
Neutrophils are pot…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
\*For patients of group 1:
* Patients with systemic sclerosis (ACR-EULAR Criteria)
* Patients taking care of in internal medicine or in dermatology department's of the university hospital of Reims
* Patients consenting to participate to the study
* Patients enrolled in the nati…
Contacts